Kybele is a global leader in health system strengthening, internationally recognized for improving the quality and safety of health care during childbirth in low- and middle-income countries. Kybele’s team consists of high-level technical experts in anesthesia, obstetric and neonatal clinical care and in systems-level quality improvement. We establish partnerships with Health Ministries and ground-level local leaders to develop innovative, cost effective solutions to local healthcare problems. Our rigorous approach has achieved high impact results, chronicled in over 25 peer-reviewed publications. Since its formation in 2001, Kybele has successfully implemented multifaceted programs with sustained impact in 13 countries in Africa and Eastern Europe with over $3 million in multilateral, government, institution, and foundation grant funding.